Ingredient 1 of 3
L-Citrulline DL-Malate in BloodPril: The Amino Acid That Becomes Arginine
L-citrulline DL-malate is citrulline bound to malic acid, and it is listed first in BloodPril's 500 mg blend. The body turns citrulline into arginine, the raw material for nitric oxide. Research on citrulline for blood pressure exists but is small, and the label gives no citrulline amount. Its cautions follow arginine's (Mayo Clinic, L-arginine).
Written by the BloodPril editorial teamUpdated
The basics
What is L-citrulline?
L-citrulline is an amino acid your body makes on its own. It takes its name from the watermelon, where it was first found.
Unlike most amino acids, citrulline is not used to build proteins. Its main job is as a go-between in two of the body's chemical cycles. One of them clears nitrogen waste. The other makes nitric oxide. In BloodPril it is the first of three ingredient forms, and the only one that is not arginine.
| Label name | L-Citrulline dl-Malate |
|---|---|
| Scientific name | Amino acid bound to malic acid |
| What it is | Amino acid salt |
| Position in the list | 1 of 3 (labels list blend ingredients from most to least by weight) |
| Per capsule | Not disclosed (part of the 500 mg blend) |
| Amount used in research | No studied dose confirmed by a source we could open |
| Strength of evidence | Not rated: no study page opened |
| Traditional or marketed use | The body turns it into arginine, the building block of nitric oxide |
| Main caution | It becomes arginine, so the arginine cautions apply: ask a doctor if you take blood pressure drugs, nitrates or ED medicine. |
The profile above comes from the BloodPril label and the sources linked in its caption. No individual amount is printed, so the per-capsule row stays blank.
The label name
What does citrulline DL-malate mean?
It means L-citrulline bound to malic acid. The malate is a partner molecule, not a second active ingredient.
Malic acid is the sour acid in apples and many other fruits. Its salt form is called malate. Your cells also make malate as part of their everyday energy cycle.
The letters "DL" describe the malic acid, not the citrulline. Malic acid comes in two mirror-image shapes, called D and L. A DL-malate contains both. The citrulline itself stays the L form, which is the form the body uses.
The malate has weight of its own. So the "L-Citrulline dl-Malate" share of the blend is not all citrulline. Part of it is malic acid. The label does not print either figure.
In the body
How does the body turn citrulline into arginine?
Mostly in the kidneys. Citrulline travels there in the blood, and kidney cells convert it into L-arginine.
- Swallowed
The capsule shell dissolves. The citrulline and the malate come apart in the gut.
- Absorbed
Citrulline passes into the bloodstream and travels around the body.
- Converted
The kidneys turn citrulline into L-arginine, the same amino acid the other two BloodPril forms supply.
- Used
Cells lining the blood vessels can use that arginine to make nitric oxide. Each time they do, citrulline is released again, so the two keep cycling.
That cycle is why citrulline is often sold next to arginine. It is basic biochemistry, not proof that a 500 mg blend changes anything you can measure. The L-arginine HCl profile covers what arginine does once it is made.
Evidence
Does L-citrulline help blood pressure?
Research on citrulline and blood pressure exists, but it is small. We could not open a study to check its numbers, so we quote none.
| Question | What we can say | Basis |
|---|---|---|
| Does the body make arginine from it? | Yes | Basic biochemistry |
| Is there blood pressure research? | Yes, but small | Published studies we could not open |
| What dose did studies use? | Not verified | No study page opened |
| How much is in one capsule? | Not published | Label shows only the 500 mg blend |
| Has BloodPril been tested? | No published trial | None found |
| Which cautions apply? | Arginine's | (Mayo Clinic, L-arginine) |
We would rather leave a cell empty than fill it with a number we have not read. If a study page becomes available to us, this table will be updated with its dose and result.
Forms
Citrulline malate vs L-citrulline: which form is in BloodPril?
BloodPril uses the malate form. Both forms deliver the same L-citrulline; they differ in the partner and in how they are marketed.
L-citrulline
The amino acid on its own. Every milligram on a label like this is citrulline. No partner molecule is attached.
Citrulline DL-malate
Citrulline bound to malic acid. Part of the weight is malate. Most products with this form are sold to gym users for workouts.
BloodPril is not dosed or labeled for exercise. Its label line is "Blood Pressure Support", and the asterisk leads to the FDA statement. Read the claims behind that line on the Supplement Facts guide.
Label order
Why is citrulline listed first on the BloodPril label?
Because it is the heaviest of the three forms. Blend ingredients must be listed from most to least by weight (FDA, Labeling guide).
Being first tells you the citrulline malate outweighs each arginine form. It does not tell you by how much. It could be a slim lead or most of the capsule.
- It weighs more than the arginine AKG, which comes second.
- Its listed weight includes the malic acid partner.
- The whole blend, all three forms together, is 500 mg per capsule.
- The label allows up to 2 capsules a day, so the blend tops out at 1,000 mg.
We cannot set that against a study dose, because we have not verified one for citrulline. For arginine, see the ingredients comparison.
Safety
Is L-citrulline safe with blood pressure medicine?
Ask your doctor first. Citrulline becomes arginine in the body, so the same cautions apply.
Mayo Clinic advises against L-arginine after a recent heart attack. It warns that with nitrates or sildenafil blood pressure can fall too low, and that arginine adds to blood pressure drugs (Mayo Clinic, L-arginine). Never stop or change a dose on your own.
Bring the bottle to your next appointment so your doctor sees all three forms. The BloodPril side effects page covers the rest.
Keep reading
Where do the other two BloodPril ingredients fit?
Both are L-arginine, the amino acid citrulline turns into. They differ only in their partner molecules.
Arginine AKG comes second on the label and arginine HCl third. Pick one below, or step through all three in label order.
FAQ
L-citrulline in BloodPril: FAQ
Is citrulline DL-malate the same as citrulline malate?
Yes, in everyday use. Citrulline malate is citrulline bound to malic acid. The DL tells you the malic acid is a mix of its two mirror-image forms. The citrulline part is L-citrulline either way.
Why does BloodPril contain citrulline as well as arginine?
The bottle gives no reason. The usual one is that the body turns citrulline into arginine by a separate route, so makers pair them. That idea has not been tested in BloodPril itself.
What dose of L-citrulline did studies use?
We cannot give a verified figure. We could not open a citrulline study page, so we do not quote doses or results. We can only say the whole BloodPril blend is 500 mg per capsule, shared by three forms.
What are the benefits of citrulline malate?
It is mostly sold for workouts and for its role in making arginine and nitric oxide. Its blood pressure research is small, and BloodPril makes no measured claim for it. Treat "benefits" lists online as marketing unless they cite a study.
Is L-citrulline a nitric oxide booster?
It is a precursor: the body turns it into arginine, which cells use to make nitric oxide. Nobody has measured nitric oxide in people taking BloodPril, so calling it a booster goes beyond the evidence.
Where does L-citrulline come from in food?
Watermelon is the best-known source, and the amino acid is named after it. Your body also makes citrulline every day as part of its normal chemistry.
Is L-citrulline better than L-arginine?
Neither has been compared with the other inside BloodPril. Citrulline reaches the body's arginine supply by a detour through the kidneys, while arginine supplies it directly. The citrulline vs arginine article sets out the differences.
Who wrote this
Written and reviewed by
Plain-language pages built from the label, the sales page and linked public health sources.
Last updated . Read our editorial standards and how we check reviews. This website is run by a U.S. shop that sells BloodPril, not by the manufacturer. We earn money when you buy through our order links.
Keep reading
More about BloodPril
Citrulline vs arginine
How citrulline becomes arginine, why supplements pair the two, and how the three forms on the BloodPril label compare.
Read more
L-arginine HCl
What the HCl form is, what the arginine trials really found, and who should skip arginine.
Read more
Side effects
Interactions, the label caution and the warning signs that mean you should stop BloodPril and call a doctor.
Read moreBloodPril U.S. shop
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